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1160 andrew gelman stats-2012-02-09-Familial Linkage between Neuropsychiatric Disorders and Intellectual Interests


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Introduction: When I spoke at Princeton last year, I talked with neuroscientist Sam Wang, who told me about a project he did surveying incoming Princeton freshmen about mental illness in their families. He and his coauthor Benjamin Campbell found some interesting results, which they just published : A link between intellect and temperament has long been the subject of speculation. . . . Studies of the artistically inclined report linkage with familial depression, while among eminent and creative scientists, a lower incidence of affective disorders is found. In the case of developmental disorders, a heightened prevalence of autism spectrum disorders (ASDs) has been found in the families of mathematicians, physicists, and engineers. . . . We surveyed the incoming class of 2014 at Princeton University about their intended academic major, familial incidence of neuropsychiatric disorders, and demographic variables. . . . Consistent with prior findings, we noticed a relation between intended academ


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1 When I spoke at Princeton last year, I talked with neuroscientist Sam Wang, who told me about a project he did surveying incoming Princeton freshmen about mental illness in their families. [sent-1, score-0.7]

2 He and his coauthor Benjamin Campbell found some interesting results, which they just published : A link between intellect and temperament has long been the subject of speculation. [sent-2, score-0.156]

3 Studies of the artistically inclined report linkage with familial depression, while among eminent and creative scientists, a lower incidence of affective disorders is found. [sent-6, score-1.461]

4 In the case of developmental disorders, a heightened prevalence of autism spectrum disorders (ASDs) has been found in the families of mathematicians, physicists, and engineers. [sent-7, score-1.281]

5 We surveyed the incoming class of 2014 at Princeton University about their intended academic major, familial incidence of neuropsychiatric disorders, and demographic variables. [sent-11, score-1.209]

6 Consistent with prior findings, we noticed a relation between intended academic majors and ASDs. [sent-15, score-0.406]

7 Looking for relations between other neuropsychiatric disorders and academic interest we also noted a heightened prevalence of bipolar disorder, major depressive disorder and substance abuse in the families of those pursuing the humanities. [sent-16, score-1.882]

8 A composite score based on these four heritable disorders was strongly correlated with a student’s intended academic major. [sent-17, score-0.911]

9 Thus, familial risk toward a spectrum of psychopathologies can predict propensity toward technical versus humanist interests. [sent-18, score-0.766]

10 When I spoke with Sam last year we discussed various ways to analyze the data as well as various interpretations of the results, but I don’t actually remember any of our conversation except for the bit where he described to me how they conducted their study. [sent-19, score-0.373]


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