nips nips2001 nips2001-2 nips2001-2-reference knowledge-graph by maker-knowledge-mining
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Author: Ádám Kepecs, S. Raghavachari
Abstract: Neurons receive excitatory inputs via both fast AMPA and slow NMDA type receptors. We find that neurons receiving input via NMDA receptors can have two stable membrane states which are input dependent. Action potentials can only be initiated from the higher voltage state. Similar observations have been made in several brain areas which might be explained by our model. The interactions between the two kinds of inputs lead us to suggest that some neurons may operate in 3 states: disabled, enabled and firing. Such enabled, but non-firing modes can be used to introduce context-dependent processing in neural networks. We provide a simple example and discuss possible implications for neuronal processing and response variability. 1
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